Resource Library

Vetted articles, videos, podcasts, and tools organised by topic so you can find what you need, gently.

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Disclosure: Some links in this library are affiliate links — if you purchase through them, we may earn a small commission at no extra cost to you. This helps keep Migraine & Me free for everyone. We only ever recommend things we genuinely believe in.

Category 1

Understanding Migraine

What migraine is, what triggers it, and how it affects the brain and body.

Understanding Triggers

3 resources
3 resources

A plain-language guide to migraine medications

Article

From triptans to CGRP inhibitors an honest overview of the medications available, how they work, and what to ask your GP.

Migraine Again podcast treatment deep dives

Podcast

Weekly conversations with neurologists and migraine specialists about the latest research, treatment options, and patient experiences.

Preventive vs acute treatment: understanding the difference

Article

Many people don't know they may qualify for preventive treatment. This guide explains the options and when to talk to your doctor.

Category 2

Treatments & Relief

Current and emerging treatment options, medications, and prevention strategies.

New Migraine Treatments

5 resources

CGRP and migraine: from bench to bedside

Nature Reviews Neurology, 2021

A landmark review in Nature Reviews Neurology tracing the journey of CGRP from basic science to approved monoclonal antibody therapies, explaining how CGRP became the most important migraine drug target of the last two decades.

Gepants for acute and preventive migraine treatment: a narrative review

PubMed 2022

A comprehensive review of rimegepant, ubrogepant, atogepant, and zavegepant, the new generation of oral CGRP receptor antagonists, covering their pharmacology, clinical trial results, safety, and comparison with triptans and monoclonal antibodies.

Efficacy of CGRP monoclonal antibodies and gepants for migraine prevention: a systematic review and network meta-analysis

Cephalalgia, 2023

The most rigorous head-to-head comparison of all approved CGRP therapies, synthesising phase 3 randomised controlled trial data across erenumab, eptinezumab, fremanezumab, galcanezumab, atogepant, and rimegepant.

2025 highlights in new targets for migraine treatment

Cephalalgia, 2026

A 2026 state-of-the-field review establishing PACAP signalling as an independent migraine pathway from CGRP, with new monoclonal antibody treatments showing significant reduction in monthly migraine days and expanding treatment options for refractory patients.

Forecasting migraine with machine learning from mobile health data

Journal of Headache and Pain, 2026

A March 2026 clinical study demonstrating that time-series machine learning applied to wearable and mobile health data can predict migraine attacks with good accuracy, opening the door to personalised early warning systems.

Category 3

Science & Genetics

The biology, genetics, and neuroscience behind migraine, plus the latest research.

Migraine Genetics

5 resources

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci

PubMed 2022

The largest migraine genome-wide association study to date, identifying 123 distinct genetic risk loci including novel drug targets such as CGRP and the serotonin 5-HT1F receptor, confirming migraine as a complex neurovascular genetic disorder.

Genetics of migraine: where are we now?

PubMed 2023

A comprehensive 2023 review covering monogenic and polygenic migraine, the role of CGRP, over 180 known genetic variants, and the shared genetic basis between migraine and comorbidities including depression and high blood pressure.

Genetics of migraine aura: an update

PubMed 2020

A focused 2020 review examining the genetic underpinnings of migraine with aura, including monogenic syndromes such as familial hemiplegic migraine, CADASIL, and findings from genome-wide association studies specific to aura subtypes.

New and sex-specific migraine susceptibility loci from a multiethnic genome-wide meta-analysis

PubMed 2021

A landmark 2021 study analysing 554,569 individuals across diverse ethnic groups including East Asian, African American, and Hispanic populations, identifying new migraine loci and sex-specific genetic risk factors.

The dawn and advancement of the knowledge of the genetics of migraine

PubMed 2024

A 2024 chronological review tracing the evolution of migraine genetics research from early twin studies through candidate gene studies, linkage analyses, and genome-wide association studies, covering both migraine with and without aura.

New Research

Ion Channels & New Pharmacological Targets

Cutting-edge research from high-profile journals published within the last three years, focusing on ion channel biology and emerging drug targets beyond CGRP.

Ion Channels & New Pharmacological Targets

6 resources

A monoclonal antibody to PACAP for migraine prevention

New England Journal of Medicine, 2024

A landmark phase 2 randomised controlled trial published in the NEJM showing that Lu AG09222, a monoclonal antibody targeting PACAP, significantly reduced monthly migraine days in patients for whom CGRP therapies had failed — establishing PACAP as a major new treatment target.

Targeting the PACAP-38 pathway: an emerging therapeutic strategy for migraine prevention

PubMed 2024

A focused review of PACAP-38 and its receptors in the trigeminovascular system, evaluating the clinical evidence for monoclonal antibodies targeting this pathway as a new and distinct treatment avenue from CGRP-based therapies.

The ATP-sensitive potassium channel (K-ATP) is a novel target for migraine drug development

PubMed 2023

Presents compelling evidence that K-ATP channels are directly implicated in migraine pathogenesis. Opening these channels with levcromakalim is the most potent migraine trigger ever tested, making K-ATP blockade a promising new drug development target.

Targeting nociceptive neurons and transient receptor potential channels for the treatment of migraine

PubMed 2023

Reviews the role of TRP ion channels in migraine nociception, discussing TRPC4 and related channels as novel pharmacological targets, and how targeting peripheral sensory neurons offers a promising new approach beyond existing treatments.

Migraine treatment: towards new pharmacological targets

PubMed 2023

A comprehensive review identifying multiple emerging drug targets beyond CGRP, including PACAP, adrenomedullin, amylin, K-ATP receptors, large-conductance calcium-sensitive potassium channels, and purinergic pathways, for patients who do not respond to existing therapies.

Migraine is a dysfunction of neuronal potassium ion channels

PubMed 2025

A 2025 review establishing that potassium channel dysfunction across K-ATP, K2P (TRESK and TREK-1), and voltage-gated channels is central to migraine pathogenesis, identifying multiple new druggable targets currently in preclinical trials.

Migraine Across the Lifespan: Children, Teenagers, Women, Older Adults and Men

14 resources

Migraine and the menstrual cycle in teenage girls: does it change at puberty?

PubMed 2020

A 2020 clinical study of girls aged 7 to 18 showing that migraine frequency increases significantly after puberty and is closely linked to the menstrual cycle. Menstrual migraine attacks in teenagers tend to be longer, more severe, and more resistant to treatment than attacks at other times of the month.

Migraine is the most disabling neurological disease among children and adolescents

Cephalalgia, 2024

Based on the GBD 2021 analysis in Lancet Neurology, this 2024 call to action establishes that migraine affects 1.16 billion people and ranks as the number one cause of disability in children and adolescents worldwide, ahead of all other neurological conditions.

Global burden of headache disorders: innovations, disparities, and priorities for action

The Lancet Neurology, 2025

The most recent Lancet Neurology GBD 2023 analysis finding nearly 2.9 billion people affected by headache disorders worldwide, with migraine driving 90% of the burden and women having a disability rate more than twice that of men.

Migraine in men

Journal of Headache and Pain, 2025

A 2025 narrative review establishing that migraine in men is widely underdiagnosed because men often present with atypical symptoms that do not match standard criteria. Covers male-specific triggers, hormonal influences including testosterone, comorbidities, and the need for individualised treatment approaches for men.

Sex-related disparities in migraine recognition and management

Journal of Headache and Pain, 2025

A 2025 study of 1,130 migraine patients showing that men are significantly less likely than women to receive a correct diagnosis before specialist referral, with men more likely to present with pressing rather than pulsating headache, leading to systematic underdiagnosis in routine care.

Migraine in older adults

The Lancet Neurology, 2023

A comprehensive 2023 Lancet Neurology review covering the diagnosis, clinical characteristics, and treatment of migraine in people over 60, including how presentation differs from younger adults, the risk of stroke, and treatment considerations in an ageing population.

Patterns of migraine in postmenopausal women: a systematic review

PubMed 2021

A 2021 systematic review examining how migraine changes after menopause, addressing the common myth that it always improves, the role of oestrogen withdrawal, hormonal therapy interactions, and what the evidence says about managing migraine in postmenopausal women.

Migraine: NIH National Institute of Neurological Disorders and Stroke

NIH

The official NIH resource on migraine covering symptoms, causes, diagnosis, treatment options, and the latest federally funded research into brain circuits, neurotransmitters, and new medicines.

Migraine: MedlinePlus NIH Health Information

NIH

A comprehensive NIH MedlinePlus guide to migraine covering symptoms, triggers, treatments including natural approaches such as riboflavin and magnesium, and links to authoritative resources.

Migraine Trainer: NIH toolkit for teens and parents

NIH

An NIH developed digital toolkit helping teenagers aged 13 and older understand their migraine causes and build an individual management plan together with their parents and healthcare providers.

Category 4

Mental Health & Wellbeing

Emotional support, mental health resources, lifestyle, and daily living with migraine.

Mental Health & Emotional Support

5 resources

Migraine and mental health: managing anxiety and depression

Article

A compassionate patient guide from the American Migraine Foundation exploring the well-established link between migraine and mental health conditions, with practical advice on seeking support and treatment.

The migraine-anxiety comorbidity among migraineurs: a systematic review

PubMed 2021

A 2021 systematic review synthesising evidence from thousands of patients on the prevalence and nature of anxiety comorbidity in migraine, confirming that anxiety disorders occur at significantly higher rates in people with migraine than the general population.

Psychiatric comorbidities of migraine

PubMed 2024

A 2024 clinical handbook chapter providing an authoritative overview of migraine comorbidity with major depressive disorder, anxiety disorders, and sleep disorders, with guidance on how these co-existing conditions complicate diagnosis and treatment.

Improvement of comorbid anxiety and depression with CGRP monoclonal antibodies

PubMed 2024

A 2024 review of 17 clinical studies examining whether CGRP-targeted monoclonal antibodies (erenumab, fremanezumab, galcanezumab) also improve comorbid anxiety and depression in migraine patients, with implications for treatment selection.

Flags for Headache: patient stories from the National Mall installation

Advocacy

Tens of thousands of purple flags installed on the National Mall in 2025, each representing a person with a disabling headache disorder. Real patient voices, caregiver stories, and advocate experiences shared at the event.

Lifestyle & Wellbeing

3 resources

Sleep and migraine: the complicated relationship

Article

Too little sleep triggers attacks. Too much does too. Here's what the science says about finding your sleep sweet spot.

Gentle yoga for migraine relief

Video

A 20-minute low-light, low-intensity yoga session designed specifically for people recovering from or trying to prevent a migraine attack.

Eating well with migraine: a balanced approach

Article

Diet advice for migraine can be overwhelming and contradictory. This guide from the American Migraine Foundation focuses on sustainable, evidence-informed dietary choices.

Workplace & Daily Life

3 resources

How to talk to your employer about migraine

Article

A practical guide to disclosing your condition, requesting workplace adjustments, and knowing your rights, including a downloadable workplace accommodations guide verified by headache specialists.

Screen time, lighting, and your migraine

Article

Practical tips for adjusting your workspace, screen settings, and lighting to reduce migraine triggers during the workday.

Miles for Migraine: patient support groups and advocacy toolkit

Tool

A US nonprofit offering community support groups, advocacy training, education days, and youth programs for people living with migraine and their families.

Category 5

Advocacy & Policy

US organisations fighting for better care, research funding, and federal recognition of migraine.

Alliance for Headache Disorders Advocacy

3 resources

AHDA: advocating for 40 million Americans with headache disorders

Advocacy

The only US nonprofit focused solely on federal policy and systems change for people living with disabling headache disorders, working with patients, clinicians, and researchers to drive lasting legislative change.

The HEADACHE Act: landmark federal legislation for migraine

Advocacy

The first federal bill focused exclusively on headache diseases, aiming to close gaps in screening, research, workforce training, and disability protections for the over 40 million Americans living with headache disorders.

Headache on the Hill: add your voice to Congress

Advocacy

A national advocacy event held twice a year where patients, caregivers, and health professionals meet with members of Congress to push for better care, more research funding, and federal policies that reflect the needs of the headache community.

Category 6

Tools & Apps

Practical tools to help you track, manage, and understand your migraine.

Category 7

Migraine-Friendly Products

Products that may help reduce symptoms, sensitivity, and the impact of migraine on daily life. Some links below are affiliate links — we may earn a small commission if you purchase, at no extra cost to you. We only recommend products we genuinely believe in. Medications listed are over-the-counter only. Always consult a qualified healthcare provider before starting any medication.

Migraine-Friendly Products

14 resources

FL-41 tinted glasses for light sensitivity

Product

Specially tinted glasses designed for people with migraine-related light sensitivity. FL-41 lenses filter the wavelengths of light most likely to trigger and worsen attacks.

Magnesium glycinate supplement

Product

Magnesium deficiency is linked to migraine. Magnesium glycinate is one of the most bioavailable forms and is widely recommended as a first-line preventive supplement.

Riboflavin (Vitamin B2) 400mg

Product

Clinical studies support riboflavin at 400mg daily as a migraine prevention supplement. It is safe, affordable, and recommended by the American Headache Society.

Blackout sleep mask

Product

A high-quality blackout sleep mask blocks all light during an attack and improves sleep quality — both critical for people living with migraine.

Migraine ice cap and cold therapy wrap

Product

Cold therapy applied to the head and neck is one of the most widely used non-medication approaches for relieving migraine pain during an acute attack.

Blue light blocking screen filter

Product

A physical screen filter reduces blue light and glare from monitors — a practical workplace solution for migraine sufferers who spend time in front of screens.

Category 8

Books & Reading

A curated selection of books on migraine — from science and diet to personal stories and tracking journals. Links are Amazon affiliate links and help support Migraine & Me at no extra cost to you.

Books & Reading

14 resources

The Headache: The Science of a Most Confounding Affliction

Book

By Tom Zeller Jr. A deeply reported, moving, and frequently surprising journey into the science of migraine and cluster headache — weaving personal suffering, history, biology, and cutting-edge research. Praised by the New Yorker and called "required reading for anyone with a head" by Mary Roach.

The Mediterranean Migraine Diet

Book

By Alicia Wolf and Dr. Shin C. Beh. A science-based roadmap using the Mediterranean diet to control migraine symptoms and transform brain health. Highly rated and evidence-informed.

The Migraine Brain

Book

By Dr. Carolyn Bernstein. A comprehensive breakthrough guide covering triggers, hormones, mental health, sleep, nutrition, and wellness for fewer headaches and better health.

Heal Your Headache

Book

By Dr. David Buchholz. A landmark book from Johns Hopkins on the 1-2-3 program for taking charge of your pain — one of the most recommended books by headache specialists.

The Migraine Relief Plan Cookbook

Book

By Stephanie Weaver MPH. More than 100 anti-inflammatory recipes for managing headaches and living a healthier life. A practical kitchen companion for anyone using diet to reduce migraine frequency and severity. Published July 2022.

Migraine Tracker Journal

Journal

A daily headache diary to identify triggers, pain levels, duration, symptoms, and relief measures. A practical companion for anyone managing migraine day to day.

Migraine Tracker for Kids

Journal

A simple headache diary designed specifically for children and teenagers to track triggers, pain levels, symptoms, and relief measures in a gentle, age-appropriate format.

Green light therapy lamp for migraine

Product

Emerging clinical research suggests that narrow-band green light may significantly reduce migraine pain intensity and frequency. A dedicated green light therapy lamp provides the specific wavelength shown in studies to be the most tolerable during attacks.

Migraine tracker and headache calendar journal

Product

A dedicated migraine tracking journal to log attack dates, duration, pain levels, triggers, and medications. Tracking patterns over time is one of the most effective ways to identify your personal triggers and communicate with your doctor.

Migraine relief medication

Product

An over-the-counter migraine relief option formulated specifically for migraine symptoms including head pain, nausea sensitivity, and light sensitivity. Always read the label and consult your healthcare provider before use.

Migraine medicine

Product

An over-the-counter option for migraine relief. For best results, take at the first sign of an attack. Always consult your doctor if you experience frequent migraines or if over-the-counter medications are not providing adequate relief.

Prescription migraine medications via Amazon Pharmacy

Pharmacy

Amazon Pharmacy is a licensed US pharmacy service where you can fill valid prescriptions for migraine medications including triptans and newer CGRP treatments. A valid prescription from your doctor is required. We do not recommend any specific prescription drug — always follow your healthcare provider's guidance.

Migraine Journal: Headache Diary Tracker for Children and Teenagers

Journal

An easy-to-use headache diary designed specifically for children and teenagers. Helps young migraine sufferers track attacks, identify triggers including menstrual patterns, record pain levels, and share information with their doctor or parents.

The Woman's Guide to Managing Migraine

Book

By Susan Hutchinson MD. A comprehensive guide to understanding the hormone connection in migraine, covering puberty, menstruation, pregnancy, and menopause. Essential reading for teenage girls, young women, and their parents seeking to understand why hormones trigger migraine.

Not Tonight: Migraine and the Politics of Gender and Health

Book

By Joanna Kempner. A groundbreaking examination of how migraine has been shaped by gender politics and medical bias. Explores why migraine is so often dismissed, misunderstood, and undertreated — and what that reveals about health inequity for women.

Dear Migraine: Essays, Poems and Art by 64 Contributors

Book

By Miles for Migraine. A powerful and moving collection of essays, poems, and artwork by 64 people living with migraine and headache disorders. Raw, honest, and deeply human — this book captures what it truly feels like to live with this condition in ways that no medical text can.

Migraine and Mia

Book

By Kat Harrison. A children's book that helps young readers understand what migraine feels like from the inside. A gentle, empathetic story for children living with migraine and for parents, teachers, and siblings who want to understand what their child is going through.

Comprehensive Migraine Management

Book

Edited by Teshamae S. Monteith, Nina Riggins, and Peter J. Goadsby — three of the world's leading headache neurologists. A rigorous clinical reference covering the full spectrum of migraine diagnosis, pathophysiology, and treatment. Ideal for patients who want to understand the science behind their condition at the highest level.

Very Well Magazine Special Edition: Understanding Migraines

Magazine

By Very Well. A special edition covering new science, new solutions, the many forms of migraine, finding relief, better sleep, and easier days. Accessible, well-researched, and written for people living with migraine rather than medical professionals.

Tools & Apps

3 resources

N1-Headache clinical-grade tracking

Tool

A research-grade app that helps you find your personal migraine patterns using a systematic, trial-based approach.

f.lux automatic screen colour adjustment

Tool

A free app that adjusts your screen's colour temperature based on the time of day, reducing blue light exposure that can trigger attacks.

Weather trigger checker

Tool

A weather app designed for migraine sufferers that flags days with high barometric pressure changes a common but overlooked trigger.

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